RPAIN antibody (C-Term)

Catalog No. ABIN6990702

This anti-RPAIN antibody is a Rabbit Polyclonal antibody detecting RPAIN in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for RPAIN antibody (C-Term) (ABIN6990702)

Target: RPAIN (RPA Interacting Protein (RPAIN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPAIN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RPAIN Antibody

Binding Specificity: C-Term

Purification: RPA Interacting Protein Antibody is affinity chromatography purified via peptide column.

Immunogen: RPA IP antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human RPA IP. The immunogen is located within the last 50 amino acids of RPA Interacting Protein.

Isotype: IgG

Application Details

Application Notes: RPA Interacting Protein antibody can be used for detection of RPA Interacting Protein by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RPA Interacting Protein Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: RPA Interacting Protein antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for RPAIN

Target: RPAIN (RPA Interacting Protein (RPAIN))

Alternative Name: RPA Interacting Protein

Background: RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.

Gene ID: 84268

NCBI Accession: NP_001028174

UniProt: Q86UA6

Pathways: Protein targeting to Nucleus