FEZ2 antibody (C-Term)

Catalog No. ABIN6990828

Product Details anti-FEZ2 Antibody

Target: FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))

Binding Specificity: C-Term

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEZ2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: FEZ2 Antibody is affinity chromatography purified via peptide column.

Immunogen: FEZ2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human FEZ2. The immunogen is located within the last 50 amino acids of FEZ2.

Isotype: IgG

Application Details

Application Notes: FEZ2 antibody can be used for the detection of FEZ2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunoflourescence starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: FEZ2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: FEZ2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FEZ2

Target: FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))

Alternative Name: FEZ2 (FEZ2 Products)

Background: FEZ2 Antibody: Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.

Gene ID: 9637

NCBI Accession: NP_001036013

UniProt: Q9UHY8