ELOVL6 antibody (N-Term)

Catalog No. ABIN6990894

This anti-ELOVL6 antibody is a Rabbit Polyclonal antibody detecting ELOVL6 in WB, ELISA, IHC (p) and IF. Suitable for Human, Mouse and Rat.

Quick Overview for ELOVL6 antibody (N-Term) (ABIN6990894)

Target: ELOVL6 (ELOVL Fatty Acid Elongase 6 (ELOVL6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-ELOVL6 Antibody

Binding Specificity: N-Term

Purification: ELOVL6 Antibody is affinity chromatography purified via peptide column.

Immunogen: ELOVL6 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of the human ELOVL6. The immunogen is located within the first 50 amino acids of ELOVL6.

Isotype: IgG

Application Details

Application Notes: ELOVL6 antibody can be used for detection of ELOVL6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ELOVL6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ELOVL6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ELOVL6

Target: ELOVL6 (ELOVL Fatty Acid Elongase 6 (ELOVL6))

Alternative Name: ELOVL6

Background: ELOVL6 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Molecular Weight: Predicted: 29 kDa

Observed: 28 kDa

Gene ID: 79071

NCBI Accession: NP_076995

UniProt: Q9H5J4