CPEB1 antibody (N-Term)

Catalog No. ABIN6990938

The Rabbit Polyclonal anti-CPEB1 antibody is suitable to detect CPEB1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for CPEB1 antibody (N-Term) (ABIN6990938)

Target: CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPEB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CPEB1 Antibody

Binding Specificity: AA 50-100, N-Term

Purification: CPEB1 Antibody is affinity chromatography purified via peptide column.

Immunogen: CPEB1 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human CPEB1. The immunogen is located within amino acids 50 - 100 of CPEB1.

Isotype: IgG

Application Details

Application Notes: CPEB1 antibody can be used for detection of CPEB1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CPEB1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CPEB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CPEB1

Target: CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))

Alternative Name: CPEB1

Background: CPEB1 Antibody: CPEB1 is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly(A) elongation and promotes polyadenylation-induced translation. CPEB1 mediates many diverse biological processes such as germ cell development, cell division and senescence, and synaptic plasticity. Recently, it was discovered that CPEB1 is involved in beta-catenin mRNA translation and cell migration in astrocytes as well as regulating hypoxia-inducible factor (HIF)-1 expression, demonstrating the wide range of processes in which CPEB1 plays a role. At least four isoforms of CPEB1 are known to exist.

Gene ID: 64506

UniProt: Q9BZB8

Pathways: Synaptic Membrane