NUP160 antibody (C-Term)

Catalog No. ABIN6990945

This anti-NUP160 antibody is a Rabbit Polyclonal antibody detecting NUP160 in WB, ELISA, IHC (p) and IF. Suitable for Mouse, Human and Rat.

Quick Overview for NUP160 antibody (C-Term) (ABIN6990945)

Target: NUP160 (Nucleoporin 160kDa (NUP160))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP160 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-NUP160 Antibody

Binding Specificity: C-Term

Purification: NUP160 Antibody is affinity chromatography purified via peptide column.

Immunogen: NUP160 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human NUP160. The immunogen is located within the last 50 amino acids of NUP160.

Isotype: IgG

Application Details

Application Notes: NUP160 antibody can be used for detection of NUP160 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: NUP160 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: NUP160 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NUP160

Target: NUP160 (Nucleoporin 160kDa (NUP160))

Alternative Name: NUP160

Background: NUP160 Antibody: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist.

Gene ID: 23279

UniProt: Q12769

Pathways: Protein targeting to Nucleus