ALDH3A2 antibody (C-Term)

Catalog No. ABIN6990973

This Rabbit Polyclonal antibody specifically detects ALDH3A2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ALDH3A2 antibody (C-Term) (ABIN6990973)

Target: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH3A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ALDH3A2 Antibody

Binding Specificity: C-Term

Specificity: At least four isoforms of Aldh3A2 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A1.

Purification: Aldh3A2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Aldh3A2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human Aldh3A2. The immunogen is located within the last 50 amino acids of Aldh3A2.

Isotype: IgG

Application Details

Application Notes: Aldh3A2 antibody can be used for detection of Aldh3A2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Aldh3A2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Aldh3A2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ALDH3A2

Target: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Alternative Name: Aldh3A2

Background: Aldh3A2 Antibody: Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.

Gene ID: 224

NCBI Accession: NP_001026976

UniProt: P51648