METTL7A antibody (AA 130-180)

Catalog No. ABIN6991013

The Rabbit Polyclonal anti-METTL7A antibody has been validated for ELISA, WB, IF and ICC. It is suitable to detect METTL7A in samples from Human and Mouse.

Quick Overview for METTL7A antibody (AA 130-180) (ABIN6991013)

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL7A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-METTL7A Antibody

Binding Specificity: AA 130-180

Specificity: At least two isoforms of MettL7A are known to exist. This antibody is predicted to not cross-react with MettL7B.

Purification: MettL7A Antibody is affinity chromatography purified via peptide column.

Immunogen: MettL7A antibody was raised against a 13 amino acid synthetic peptide near the center of human MettL7A. The immunogen is located within amino acids 130 - 180 of MettL7A.

Isotype: IgG

Application Details

Application Notes: MettL7A antibody can be used for detection of MettL7A by Western blot at 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MettL7A Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MettL7A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for METTL7A

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Alternative Name: MettL7A

Background: MettL7A Antibody: MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

Gene ID: 25840

NCBI Accession: NP_054752

UniProt: Q9H8H3