MTCH2 antibody (N-Term)

Catalog No. ABIN6991074

This anti-MTCH2 antibody is a Rabbit Polyclonal antibody detecting MTCH2 in WB, ELISA, IF and IHC (p). Suitable for Human and Mouse.

Quick Overview for MTCH2 antibody (N-Term) (ABIN6991074)

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTCH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MTCH2 Antibody

Binding Specificity: AA 80-130, N-Term

Purification: MTCH2 Antibody is affinity chromatography purified via peptide column.

Immunogen: MTCH2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MTCH2. The immunogen is located within amino acids 80 - 130 of MTCH2.

Isotype: IgG

Application Details

Application Notes: MTCH2 antibody can be used for detection of MTCH2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MTCH2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MTCH2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MTCH2

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Alternative Name: MTCH2

Background: MTCH2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.

Gene ID: 56428

NCBI Accession: NP_055157

UniProt: Q791V5