ANKRD27 antibody (AA 640-690)

Catalog No. ABIN6991210

This Rabbit Polyclonal antibody specifically detects ANKRD27 in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ANKRD27 antibody (AA 640-690) (ABIN6991210)

Target: ANKRD27 (Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD27 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ANKRD27 Antibody

Binding Specificity: AA 640-690

Purification: VARP Antibody is affinity chromatography purified via peptide column.

Immunogen: VARP antibody was raised against a 15 amino acid synthetic peptide near the center of human VARP. The immunogen is located within amino acids 640 - 690 of VARP.

Isotype: IgG

Application Details

Application Notes: VARP antibody can be used for detection of VARP by Immunohistochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: VARP Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: VARP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ANKRD27

Target: ANKRD27 (Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27))

Alternative Name: VARP

Background: VARP Antibody: The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.

Gene ID: 84079

NCBI Accession: NP_115515

UniProt: Q96NW4