Transmembrane Protein 70 (TMM70) (AA 150-200) antibody

Catalog No. ABIN6991293

This anti- antibody is a Rabbit Polyclonal antibody detecting in WB, ELISA, IHC (p) and IF. Suitable for Human, Mouse and Rat.

Quick Overview for Transmembrane Protein 70 (TMM70) (AA 150-200) antibody (ABIN6991293)

Target: Transmembrane Protein 70 (TMM70)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 150-200

Purification: TMEM70 Antibody is affinity chromatography purified via peptide column.

Immunogen: TMEM70 antibody was raised against a 14 amino acid synthetic peptide near the center of human TMEM70. The immunogen is located within amino acids 150 - 200 of TMEM70.

Isotype: IgG

Application Details

Application Notes: TMEM70 antibody can be used for detection of TMEM70 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMEM70 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TMEM70 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details

Target: Transmembrane Protein 70 (TMM70)

Alternative Name: TMEM70

Background: TMEM70 Antibody: TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.

Gene ID: 54968

NCBI Accession: NP_060336

UniProt: Q9BUB7