SAE1 antibody (C-Term)

Catalog No. ABIN6991336

This Rabbit Polyclonal antibody specifically detects SAE1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SAE1 antibody (C-Term) (ABIN6991336)

Target: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SAE1 Antibody

Binding Specificity: AA 240-290, C-Term

Purification: SAE1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SAE1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human SAE1. The immunogen is located within amino acids 240 - 290 of SAE1.

Isotype: IgG

Application Details

Application Notes: SAE1 antibody can be used for detection of SAE1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SAE1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SAE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SAE1

Target: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Alternative Name: SAE1

Background: SAE1 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.

Molecular Weight: Predicted: 38 kDa

Observed: 39 kDa

Gene ID: 10055

NCBI Accession: NP_005491

UniProt: Q9UBE0