SNRPE antibody (AA 330-380)

Catalog No. ABIN6991349

The Chicken Polyclonal anti-SNRPE antibody has been validated for WB and ELISA. It is suitable to detect SNRPE in samples from Human, Mouse and Rat.

Quick Overview for SNRPE antibody (AA 330-380) (ABIN6991349)

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This SNRPE antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SNRPE Antibody

Binding Specificity: AA 330-380

Purification: B-raf Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-B-raf antibody was raised against a peptide corresponding to 18 amino acids near the center of human B-raf. The immunogen is located within amino acids 330 - 380 of B-raf.

Isotype: IgY

Application Details

Application Notes: WB: 0.5-2 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: B-raf Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: B-raf antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SNRPE

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Alternative Name: B-raf

Background: B-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance.

Molecular Weight: Predicted: 94kD

Observed: 94 kD kDa

Gene ID: 673

UniProt: P15056

Pathways: Ribonucleoprotein Complex Subunit Organization, Hepatitis C