SH3RF2 antibody (C-Term)

Catalog No. ABIN6991394

The Rabbit Polyclonal anti-SH3RF2 antibody is suitable to detect SH3RF2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC (p) and IF.

Quick Overview for SH3RF2 antibody (C-Term) (ABIN6991394)

Target: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3RF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-SH3RF2 Antibody

Binding Specificity: C-Term

Purification: SH3RF2 Antibody is affinity chromatography purified via peptide column.

Immunogen: SH3RF2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SH3RF2. The immunogen is located within the last 50 amino acids of SH3RF2.

Isotype: IgG

Application Details

Application Notes: SH3RF2 antibody can be used for detection of SH3RF2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SH3RF2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SH3RF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SH3RF2

Target: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Alternative Name: SH3RF2

Background: SH3RF2 Antibody: Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2 associates with protein phosphatase 1 (PP1) and is expressed primarily in heart and testis tissue. Recombinant SH3RF2 enhanced PP1 enzymatic activity and antagonized the ability of phopho-inhibitor-1 or -2 to inhibit PP1, suggesting that SH3RF2 may play a role working with PP1 in cardiac functions.

Gene ID: 153769

NCBI Accession: NP_689763

UniProt: Q8TEC5