SYNPO2L antibody (N-Term)

Catalog No. ABIN6991444

This Rabbit Polyclonal antibody specifically detects SYNPO2L in WB, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for SYNPO2L antibody (N-Term) (ABIN6991444)

Target: SYNPO2L (Synaptopodin 2-Like (SYNPO2L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNPO2L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-SYNPO2L Antibody

Binding Specificity: AA 140-190, N-Term

Purification: SYNPO2L Antibody is affinity chromatography purified via peptide column.

Immunogen: SYNPO2L antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SYNPO2L. The immunogen is located within amino acids 140 - 190 of SYNPO2L.

Isotype: IgG

Application Details

Application Notes: SYNPO2L antibody can be used for detection of SYNPO2L by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SYNPO2L Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SYNPO2L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SYNPO2L

Target: SYNPO2L (Synaptopodin 2-Like (SYNPO2L))

Alternative Name: SYNPO2L

Background: SYNPO2L Antibody: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.

Gene ID: 79933

UniProt: Q9H987