CTNNBL1 antibody (C-Term)

Catalog No. ABIN6991497

This anti-CTNNBL1 antibody is a Rabbit Polyclonal antibody detecting CTNNBL1 in WB, ELISA, IF and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for CTNNBL1 antibody (C-Term) (ABIN6991497)

Target: CTNNBL1 (Catenin, beta Like 1 (CTNNBL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNNBL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CTNNBL1 Antibody

Binding Specificity: C-Term

Specificity: CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist, this antibody will detect all but isoform b.

Purification: CTTNBL1 Antibody is affinity chromatography purified via peptide column.

Immunogen: CTTNBL1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human CTTNBL1. The immunogen is located within the last 50 amino acids of CTTNBL1.

Isotype: IgG

Application Details

Application Notes: CTTNBL1 antibody can be used for detection of CTTNBL1 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CTTNBL1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CTTNBL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CTNNBL1

Target: CTNNBL1 (Catenin, beta Like 1 (CTNNBL1))

Alternative Name: CTTNBL1

Background: CTTNBL1 Antibody: The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.

Molecular Weight: Predicted: 65 kDa

Observed: 63 kDa

Gene ID: 56259

NCBI Accession: NP_110517

UniProt: Q8WYA6

Pathways: Production of Molecular Mediator of Immune Response