CD48 antibody (AA 90-140)

Catalog No. ABIN6991511

The Rabbit Polyclonal anti-CD48 antibody is suitable to detect CD48 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for CD48 antibody (AA 90-140) (ABIN6991511)

Target: CD48

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD48 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD48 Antibody

Binding Specificity: AA 90-140

Specificity: Two isoforms of SLAMF2 are known to exist, this antibody will recognize both isoforms. SLAMF2 antibody is predicted to not cross-react with other SLAM protein family members.

Purification: SLAMF2 Antibody is affinity chromatography purified via peptide column.

Immunogen: SLAMF2 antibody was raised against a 19 amino acid synthetic peptide near the center of human SLAMF2. The immunogen is located within amino acids 90 - 140 of SLAMF2.

Isotype: IgG

Application Details

Application Notes: SLAMF2 antibody can be used for detection of SLAMF2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLAMF2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SLAMF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CD48

Target: CD48

Alternative Name: SLAMF2

Background: SLAMF2 Antibody: The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.

Gene ID: 962

NCBI Accession: NP_1769

UniProt: P09326