The Chicken Polyclonal anti-DRGX antibody (ABIN6991590) specifically detects DRGX in WB, ELISA and IF.
The antibody is reactive with Human, Mouse and Rat samples.
At least two are known to exist, DRGX antibody is predicted to not cross-react with other Homeodomain proteins.
Purification
DRGX Antibody is affinity chromatography purified via peptide column.
Immunogen
DRGX antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human DRGX. The immunogen is located within the last 50 amino acids of DRGX.
DRGX
Reactivity: Human
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
DRGX antibody can be used for detection of DRGX by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
DRGX Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
DRGX antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
DRGX
(Dorsal Root Ganglia Homeobox (DRGX))
Alternative Name
DRGX
Background
DRGX Antibody: DRGX, also known as DRG11 or PRRXL1, is a paired homeodomain transcription factor, and was initially cloned from a differential hybridization screen aimed at identifying dorsal root ganglia (DRG)-specific genes. DRGX is a key regulator of the differentiation of the spinal cord neuronal circuit dedicated to the processing of nociceptive information. DRGX is also important for the formation of the whisker-related somatosensory maps in the principal sensory nucleus of the trigeminal nerve, thalamus and somatosensory cortex.