Transglutaminase 5 antibody (C-Term)

Catalog No. ABIN6991595

The Rabbit Polyclonal anti-Transglutaminase 5 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect Transglutaminase 5 in samples from Human, Mouse and Rat.

Quick Overview for Transglutaminase 5 antibody (C-Term) (ABIN6991595)

Target: Transglutaminase 5 (TGM5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transglutaminase 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Transglutaminase 5 Antibody

Binding Specificity: C-Term

Specificity: TGM5 antibody is predicted to not cross-react with other TGase protein family members. Multiple isoforms of TGM5 are known to exist.

Purification: TGM5 Antibody is affinity chromatography purified via peptide column.

Immunogen: TGM5 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TGM5. The immunogen is located within the last 50 amino acids of TGM5.

Isotype: IgG

Application Details

Application Notes: TGM5 antibody can be used for detection of TGM5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TGM5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TGM5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Transglutaminase 5

Target: Transglutaminase 5 (TGM5)

Alternative Name: TGM5

Background: TGM5 Antibody: Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM5 belongs to the transglutaminase superfamily and catalyzes the cross-linking of proteins between glutamine and lysine residues, often resulting in stabilization of protein assemblies. TGM5 is also expressed in the human hair follicle. Defects in TGM5 are associated with acral peeling skin syndrome.

Gene ID: 9333

NCBI Accession: NP_963925

UniProt: O43548