ANKLE2 antibody (AA 280-330)

Catalog No. ABIN6991616

The Chicken Polyclonal anti-ANKLE2 antibody is suitable to detect ANKLE2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for ANKLE2 antibody (AA 280-330) (ABIN6991616)

Target: ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This ANKLE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ANKLE2 Antibody

Binding Specificity: AA 280-330

Specificity: Three isoforms of ANKLE2 are known to exist, this antibody will detect all three. ANKLE2 antibody is predicted to not cross-react with ANKLE1.

Purification: ANKLE2 Antibody is affinity chromatography purified via peptide column.

Immunogen: ANKLE2 antibody was raised against a 19 amino acid synthetic peptide near the center of human ANKLE2. The immunogen is located within amino acids 280 - 330 of ANKLE2.

Isotype: IgY

Application Details

Application Notes: ANKLE2 antibody can be used for detection of ANKLE2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ANKLE2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ANKLE2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ANKLE2

Target: ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))

Alternative Name: ANKLE2

Background: ANKLE2 Antibody: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE2 (Ankyrin repeat and LEM domain containing 2) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains three ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. The function of this protein is still under investigation.

Molecular Weight: Predicted: 121, 139, 145 kDa

Observed: 121 kDa

Gene ID: 23141

UniProt: Q86XL3