GBP6 antibody (C-Term)

Catalog No. ABIN6991646

The Rabbit Polyclonal anti-GBP6 antibody has been validated for ELISA, WB, ICC and IF. It is suitable to detect GBP6 in samples from Human and Mouse.

Quick Overview for GBP6 antibody (C-Term) (ABIN6991646)

Target: GBP6 (Guanylate Binding Protein 6 (GBP6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-GBP6 Antibody

Binding Specificity: C-Term

Specificity: GBP6 antibody is predicted to not cross-react with other GBP family members.

Purification: GBP6 Antibody is affinity chromatography purified via peptide column.

Immunogen: GBP6 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human GBP6. The immunogen is located within the last 50 amino acids of GBP6.

Isotype: IgG

Application Details

Application Notes: GBP6 antibody can be used for detection of GBP6 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: GBP6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: GBP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GBP6

Target: GBP6 (Guanylate Binding Protein 6 (GBP6))

Alternative Name: GBP6

Background: GBP6 Antibody: The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3). GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP. The precise function of GBP6 is still under investigation.

Gene ID: 163351

NCBI Accession: NP_940862

UniProt: Q6ZN66

Pathways: Cellular Response to Molecule of Bacterial Origin