RNASET2 antibody (C-Term)

Catalog No. ABIN6991661

The Rabbit Polyclonal anti-RNASET2 antibody is suitable to detect RNASET2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, ICC and IF.

Quick Overview for RNASET2 antibody (C-Term) (ABIN6991661)

Target: RNASET2 (Ribonuclease T2 (RNASET2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASET2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-RNASET2 Antibody

Binding Specificity: C-Term

Purification: RNASET2 Antibody is affinity chromatography purified via peptide column.

Immunogen: RNASET2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human RNASET2. The immunogen is located within the last 50 amino acids of RNASET2.

Isotype: IgG

Application Details

Application Notes: RNASET2 antibody can be used for detection of FOXRED2 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RNASET2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: RNASET2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for RNASET2

Target: RNASET2 (Ribonuclease T2 (RNASET2))

Alternative Name: RNASET2

Background: RNASET2 Antibody: RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.

Gene ID: 8635

NCBI Accession: NP_003721

UniProt: O00584