Myc Target 1 antibody (C-Term)

Catalog No. ABIN6991752

This anti-Myc Target 1 antibody is a Rabbit Polyclonal antibody detecting Myc Target 1 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Myc Target 1 antibody (C-Term) (ABIN6991752)

Target: Myc Target 1 (MYCT1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myc Target 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Myc Target 1 Antibody

Binding Specificity: C-Term

Specificity: At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.

Purification: MYCT1 Antibody is affinity chromatography purified via peptide column.

Immunogen: MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1. The immunogen is located within the last 50 amino acids of MYCT1.

Isotype: IgG

Application Details

Application Notes: MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MYCT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MYCT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Myc Target 1

Target: Myc Target 1 (MYCT1)

Alternative Name: MYCT1

Background: MYCT1 Antibody: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.

Molecular Weight: 26 kDa

Gene ID: 80177

NCBI Accession: NP_079383

UniProt: Q8N699