VNN3 antibody (C-Term)

Catalog No. ABIN6991763

The Rabbit Polyclonal anti-VNN3 antibody is suitable to detect VNN3 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC (p).

Quick Overview for VNN3 antibody (C-Term) (ABIN6991763)

Target: VNN3 (Vanin 3 (VNN3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VNN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-VNN3 Antibody

Binding Specificity: C-Term

Specificity: Multiple isoforms of VNN3 are known to exist.

Purification: VNN3 Antibody is affinity chromatography purified via peptide column.

Immunogen: VNN3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human VNN3. The immunogen is located within the last 50 amino acids of VNN3.

Isotype: IgG

Application Details

Application Notes: VNN3 antibody can be used for detection of VNN3 by Western blot at 0.5 and 1 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: VNN3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: VNN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for VNN3

Target: VNN3 (Vanin 3 (VNN3))

Alternative Name: VNN3

Background: VNN3 Antibody: The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.

Molecular Weight: 55 kDa

Gene ID: 55350

UniProt: Q9NY84