TSPY1S (C-Term) antibody

Catalog No. ABIN6991789

This Rabbit Polyclonal antibody specifically detects in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for TSPY1S (C-Term) antibody (ABIN6991789)

Target: TSPY1S

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Application: ELISA, Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Specificity: TSPY1S antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist, this antibody will detect only TSPY1S

Purification: TSPY1S Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal TSPY1S antibody was raised against a 13 amino acid peptide near the carboxy terminus of human TSPY1S. The immunogen is located within the last 50 amino acids of TSPY1S.

Isotype: IgG

Application Details

Application Notes: TSPY1S antibody can be used for detection of TSPY1S by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TSPY1S Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TSPY1S antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details

Target: TSPY1S

Background: TSPY1S Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

Molecular Weight: 32 kDa

Gene ID: 7258

NCBI Accession: NP_001184171

UniProt: Q01534