FOXA2 antibody (AA 280-330)

Catalog No. ABIN6991830

This anti-FOXA2 antibody is a Rabbit Polyclonal antibody detecting FOXA2 in WB, ELISA, IF and IHC (p). Suitable for Human and Mouse.

Quick Overview for FOXA2 antibody (AA 280-330) (ABIN6991830)

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FOXA2 Antibody

Binding Specificity: AA 280-330

Specificity: At least two isoforms of FOXA2 are known to exist, this antibody will detect both isoforms. FOXA2 antibody is predicted to not cross-react with other members of the FOXA protein family.

Purification: FOXA2 Antibody is affinity chromatography purified via peptide column.

Immunogen: FOXA2 antibody was raised against a 16 amino acid peptide near the center of human FOXA2 . The immunogen is located within amino acids 280 - 330 of FOXA2.

Isotype: IgG

Application Details

Application Notes: FOXA2 Antibody can be used for detection of FOXA2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: FOXA2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: FOXA2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Alternative Name: FOXA2

Background: FOXA2 Antibody: FOXA2 is one of three members of the FOXA family, a subset of the forkhead family of transcription factors which play vital roles in development. FOXA2 was initially identified through library screening as a closely related homolog of FOXA1. Both FOXA2 and FOXA1 act as transcriptional activators in adult liver and also play a role in body axis formation, neural tube patterning and definitive endoderm formation during gastrulation.

Molecular Weight: Predicted: 51 kDa

Observed: 54 kDa

Gene ID: 3170

NCBI Accession: NP_068556

UniProt: Q9Y261

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process