PRKCDBP antibody (AA 150-200)

Catalog No. ABIN6991835

The Rabbit Polyclonal anti-PRKCDBP antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect PRKCDBP in samples from Human and Mouse.

Quick Overview for PRKCDBP antibody (AA 150-200) (ABIN6991835)

Target: PRKCDBP (Protein Kinase C, delta Binding Protein (PRKCDBP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKCDBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PRKCDBP Antibody

Binding Specificity: AA 150-200

Specificity: It is predicted to not cross-react with other members of the cavin family.

Purification: PRKCDBP Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP. The immunogen is located within amino acids 150 - 200 of PRKCDBP.

Isotype: IgG

Application Details

Application Notes: PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PRKCDBP Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PRKCDBP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for PRKCDBP

Target: PRKCDBP (Protein Kinase C, delta Binding Protein (PRKCDBP))

Alternative Name: PRKCDBP

Background: PRKCDBP Antibody: The protein kinase C delta (PKC-δ,) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ, but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.

Molecular Weight: 29 kDa

Gene ID: 112464

NCBI Accession: NP_659477

UniProt: Q969G5