NUCB2 antibody (AA 260-310)

Catalog No. ABIN6991836

This anti-NUCB2 antibody is a Rabbit Polyclonal antibody detecting NUCB2 in WB, ELISA, IHC (p) and IF. Suitable for Human, Rat and Mouse.

Quick Overview for NUCB2 antibody (AA 260-310) (ABIN6991836)

Target: NUCB2 (Nucleobindin 2 (NUCB2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUCB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-NUCB2 Antibody

Binding Specificity: AA 260-310

Specificity: Nucleobindin-2 antibody is predicted to not cross-react with NUCB1.

Purification: Nucleobindin-2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Nucleobindin-2 antibody was raised against a 16 amino acid peptide near the center of human Nucleobindin-2 . The immunogen is located within amino acids 260 - 310 of Nucleobindin-2.

Isotype: IgG

Application Details

Application Notes: Nucleobindin-2 Antibody can be used for detection of Nucleobindin-2 by Western blot starting at 0.5 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Nucleobindin-2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Nucleobindin-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for NUCB2

Target: NUCB2 (Nucleobindin 2 (NUCB2))

Alternative Name: Nucleobindin-2

Background: Nucleobindin-2 Antibody: NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.

Molecular Weight: Predicted: 46 kDa

Observed: 54 kDa

Gene ID: 4925

NCBI Accession: NP_005004

UniProt: P80303