TLX2 antibody (N-Term)

Catalog No. ABIN6991867

This Rabbit Polyclonal antibody specifically detects TLX2 in WB, ELISA, IHC (p) and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for TLX2 antibody (N-Term) (ABIN6991867)

Target: TLX2 (T-Cell Leukemia Homeobox 2 (TLX2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-TLX2 Antibody

Binding Specificity: AA 20-70, N-Term

Specificity: TLX2 antibody is predicted to not cross-react with other TLX proteins.

Purification: TLX2 Antibody is affinity chromatography purified via peptide column.

Immunogen: TLX2 antibody was raised against an 18 amino acid peptide near the amino terminus of human TLX2. The immunogen is located within amino acids 20 - 70 of TLX2.

Isotype: IgG

Application Details

Application Notes: TLX2 antibody can be used for detection of TLX2 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLX2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TLX2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TLX2

Target: TLX2 (T-Cell Leukemia Homeobox 2 (TLX2))

Alternative Name: TLX2

Background: TLX2 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.

Molecular Weight: Predicted: 31 kDa

Observed: 30 kDa

Gene ID: 3196

NCBI Accession: NP_057254

UniProt: O43763