GDPD5 antibody (N-Term)

Catalog No. ABIN6991987

This Rabbit Polyclonal antibody specifically detects GDPD5 in WB, ELISA, IHC (p) and IF. It exhibits reactivity toward Human, Mouse and Ratand has been mentioned in 1 publication.

Quick Overview for GDPD5 antibody (N-Term) (ABIN6991987)

Target: GDPD5 (Glycerophosphodiester Phosphodiesterase Domain Containing 5 (GDPD5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDPD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-GDPD5 Antibody

Binding Specificity: N-Term

Specificity: GDPD5 antibody is human, mouse and rat reactive. At least three isoforms of GDPD5 are known to exist.

Purification: GDPD5 antibody is affinity chromatography purified via peptide column.

Immunogen: GDPD5 antibody was raised against an 18 amino acid peptide near the amino terminus of human GDPD5. The immunogen is located within the first 50 amino acids of GDPD5.

Isotype: IgG

Application Details

Application Notes: GDPD5 antibody can be used for detection of GDPD5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: GDPD5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: GDPD5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

References for anti-GDPD5 antibody (ABIN6991987)

Zhang, Dai, Zhao, Wang, Dou, Zhuang, Chen, Zhao et al.: "MiR-874-3p represses the migration and invasion yet promotes the apoptosis and cisplatin sensitivity via being sponged by long intergenic non-coding RNA 00922 (LINC00922) and targeting ..." in: Bioengineered, Vol. 13, Issue 3, pp. 7082-7104, (2022) (PubMed).

Target Details for GDPD5

Target: GDPD5 (Glycerophosphodiester Phosphodiesterase Domain Containing 5 (GDPD5))

Alternative Name: GDPD5

Background: The glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) protein, also known as GDE2, is a seven transmembrane, widely expressed protein (1) that is necessary for spinal motor neuron differentiation and retinoid-induced neuronal outgrowth (2,3). Altered choline phospholipid metabolism is a hallmark of cancer, and the elevated expression of GDPD5 correlates with malignant choline phospholipid metabolite profiles in human breast cancer (4).

Molecular Weight: Predicted: 40, 67 kDa

Observed: 52 kDa

Gene ID: 81544

NCBI Accession: NP_110419

UniProt: Q8WTR4