UBIAD1 antibody (C-Term)

Catalog No. ABIN6991991

The Rabbit Polyclonal anti-UBIAD1 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect UBIAD1 in samples from Human, Mouse and Rat.

Quick Overview for UBIAD1 antibody (C-Term) (ABIN6991991)

Target: UBIAD1 (UbiA Prenyltransferase Domain Containing 1 (UBIAD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBIAD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-UBIAD1 Antibody

Binding Specificity: AA 210-260, C-Term

Specificity: UBIAD1 antibody is human, mouse and rat reactive.

Purification: UBIAD1 antibody is affinity chromatography purified via peptide column.

Immunogen: UBIAD1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human UBIAD1. The immunogen is located within amino acids 210 - 260 of UBIAD1.

Isotype: IgG

Application Details

Application Notes: UBIAD1 antibody can be used for detection of UBIAD1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: UBIAD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: UBIAD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for UBIAD1

Target: UBIAD1 (UbiA Prenyltransferase Domain Containing 1 (UBIAD1))

Alternative Name: UBIAD1

Background: The UbiA prenyltransferase domain containing 1 (UBIAD1) protein , also known as TERE1, was initially identified as a down-regulated gene in transitional cell carcinoma of the bladder (1). Recently it has been shown to bind the cholesterol carrier APOE and modulate cellular cholesterol levels (2). Mutations in the UBIAD1 gene can cause Schnyder crystalline corneal dystrophy, an autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids (3).

Molecular Weight: Predicted: 37 kDa

Observed: 45 kDa

Gene ID: 29914

NCBI Accession: NP_037451

UniProt: Q9Y5Z9