Western Blotting (WB), ELISA, Immunofluorescence (IF)
Specificity
SOX17 antibody is human, mouse and rat reactive. SOX17 is predicted to not cross-react with other SOX proteins.
Purification
SOX17 antibody is affinity chromatography purified via peptide column.
Immunogen
SOX17 antibody was raised against a 16 amino acid peptide near the center of human SOX17. The immunogen is located within amino acids 240 - 290 of SOX17.
SOX17 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2). SOX17 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types, including visceral and definitive endoderm and hematopoietic cell types (3,4). SOX17 is also essential for acquisition and maintenance of arterial identity (5).