GLIS2 antibody (AA 260-310)
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- Target See all GLIS2 Antibodies
- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
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Binding Specificity
- AA 260-310
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GLIS2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- GLIS2 antibody is human, mouse and rat reactive.
- Purification
- GLIS2 antibody is affinity chromatography purified via peptide column.
- Immunogen
- GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2. The immunogen is located within amino acids 260 - 310 of GLIS2.
- Isotype
- IgG
- Top Product
- Discover our top product GLIS2 Primary Antibody
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- Application Notes
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GLIS2 antibody can be used for detection of GLIS2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- GLIS2 antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- GLIS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Target
- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
- Alternative Name
- GLIS2 (GLIS2 Products)
- Synonyms
- glis2b antibody, nkl-A antibody, xNKLb antibody, NKL antibody, NPHP7 antibody, Gli5 antibody, Klf16 antibody, Nkl antibody, glis2a antibody, nphp7 antibody, GLIS family zinc finger 2 L homeolog antibody, GLIS family zinc finger 2 antibody, GLIS family zinc finger 2 S homeolog antibody, glis2.L antibody, GLIS2 antibody, Glis2 antibody, glis2.S antibody
- Background
- GLIS2, also known as neuronal Krueppel-like, is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family (1). GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation (1,2). GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta. Mutations of GLIS2 have been suggested to be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis (3,4).
- Molecular Weight
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Predicted: 58 kDa
Observed: 60 kDa - Gene ID
- 84662
- NCBI Accession
- NP_115964
- UniProt
- Q9BZE0
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