QSOX1 antibody (AA 360-410)

Catalog No. ABIN6992133

This anti-QSOX1 antibody is a Rabbit Polyclonal antibody detecting QSOX1 in WB, ELISA, IF and IHC (p). Suitable for Human and Mouse.

Quick Overview for QSOX1 antibody (AA 360-410) (ABIN6992133)

Target: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QSOX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-QSOX1 Antibody

Binding Specificity: AA 360-410

Specificity: QSOX1 antibody is human and mouse reactive. QSOX1 antibody is predicted to not cross-react with QSOX2.

Purification: QSOX1 antibody is affinity chromatography purified via peptide column.

Immunogen: QSOX1 antibody was raised against a 17 amino acid peptide near the center of human QSOX1. The immunogen is located within amino acids 360 - 410 of QSOX1.

Isotype: IgG

Application Details

Application Notes: QSOX1 antibody can be used for detection of QSOX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: QSOX1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: QSOX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for QSOX1

Target: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Alternative Name: QSOX1

Background: The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation (1). The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia (2) and appears to protect cells against oxidative stress-induced apoptosis (3).

Molecular Weight: Predicted: 65, 82 kDa

Observed: 66 kDa

Gene ID: 5768

NCBI Accession: NP_002817

UniProt: O00391

Pathways: Cell RedoxHomeostasis