RFX1 antibody (C-Term)
Quick Overview for RFX1 antibody (C-Term) (ABIN6992144)
Target
See all RFX1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- RFX1 antibody is human specific. At least two isoforms of RFX1 are known to exist, this antibody will detect both isoforms.
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Purification
- RFX1 antibody is affinity chromatography purified via peptide column.
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Immunogen
- RFX1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RFX1. The immunogen is located within the last 50 amino acids of RFX1.
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Isotype
- IgG
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anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (AA 36-133) antibody
RFX1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (AA 896-925), (C-Term) antibodyRFX1 Reactivity: Human WB, IF Host: Rabbit Polyclonal RB30347 unconjugated
anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (AA 200-300) antibodyRFX1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (AA 38-87) antibodyRFX1 Reactivity: Human, Dog, Pig, Monkey, Bat WB Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (C-Term) antibodyRFX1 Reactivity: Human, Cow, Dog, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (AA 287-336) antibodyRFX1 Reactivity: Human, Mouse, Rat, Cow, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (AA 181-230) antibodyRFX1 Reactivity: Mouse, Rat, Cow, Dog, Guinea Pig, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (N-Term) antibodyRFX1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (C-Term) antibodyRFX1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
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Application Notes
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RFX1 antibody can be used for detection of RFX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- RFX1 antibody is supplied in PBS containing 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,4 °C
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Storage Comment
- RFX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))
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Alternative Name
- RFX1
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Background
- RFX1 is a member of the regulatory factor X protein family, which are transcription factors that contain a highly-conserved winged helix DNA binding domain and the D region found in the C-terminal part of these proteins which facilitates dimerization (1,2). RFX1 is structurally related to regulatory factors X2, X3, X4, and X5 (3). RFX1 is a regulatory factor essential for MHC class II genes expression and can bind to an inverted repeat that is required for expression of hepatitis B virus genes (4). Recent study identifies RFX1 may play a tumor suppressor role in HCC as autophagy mediator (5).
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Molecular Weight
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Predicted: 108 kDa
Observed: 125 kDa -
Gene ID
- 5989
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NCBI Accession
- NP_002909
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UniProt
- P22670
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Pathways
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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