SLC36A2 antibody (N-Term)

Catalog No. ABIN6992165

The Rabbit Polyclonal anti-SLC36A2 antibody is suitable to detect SLC36A2 in samples from Human. It has been validated for ELISA and WB.

Quick Overview for SLC36A2 antibody (N-Term) (ABIN6992165)

Target: SLC36A2 (Solute Carrier Family 36 (Proton/amino Acid Symporter), Member 2 (SLC36A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC36A2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-SLC36A2 Antibody

Binding Specificity: AA 30-80, N-Term

Specificity: SLC36A2 antibody is human specific. SLC36A2 is predicted to not cross-react with other members of the SLC36 protein family.

Purification: SLC36A2 antibody is affinity chromatography purified via peptide column.

Immunogen: SLC36A2 antibody was raised against a 15 amino acid peptide near the amino terminus of human SLC36A2. The immunogen is located within amino acids 30 - 80 of SLC36A2.

Isotype: IgG

Application Details

Application Notes: SLC36A2 antibody can be used for detection of SLC36A2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLC36A2 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SLC36A2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for SLC36A2

Target: SLC36A2 (Solute Carrier Family 36 (Proton/amino Acid Symporter), Member 2 (SLC36A2))

Alternative Name: SLC36A2

Background: SLC36A2 is a pH -dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline (1,2). Both SLC36A2 and its paralog SLC36A1 are expressed in neurons, but SLC36A2 localizes to the endoplasmic reticulum and recycling endosome, while SLC36A1 is expressed in the lysosome (2). SLC36A2 is thought to contribute to neuronal transport and sequestration of amino acids such as glycine, alanine, and proline (2). Mutations in this gene are associated with iminoglycinuria and hyperglycinuria (3).

Molecular Weight: Predicted: 53 kDa

Observed: 52 kDa

Gene ID: 153201

NCBI Accession: NP_861441

UniProt: Q495M3

Pathways: Proton Transport