Human Immunodeficiency Virus Surface Glycoprotein (HIV gp120) antibody

Catalog No. ABIN6992202

Product Details

Target: Human Immunodeficiency Virus Surface Glycoprotein (HIV gp120)

Reactivity: Human Immunodeficiency Virus (HIV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: gp120 Antibody is affinity chromatography purified via peptide column.

Immunogen: gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120.

Isotype: IgG

Application Details

Application Notes: gp120 antibody can be used for Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: gp120 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: gp120 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details

Target: Human Immunodeficiency Virus Surface Glycoprotein (HIV gp120)

Alternative Name: HIV Gp120

Target Type: Viral Protein

Background: Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

Molecular Weight: Predicted: 120 kDa

Observed: 120 kDa

Gene ID: 155971

UniProt: P04578