SARS-CoV-2 ORF8 antibody (C-Term)

Catalog No. ABIN6992307

The Rabbit Polyclonal anti-SARS-CoV-2 ORF8 antibody has been validated for ELISA, WB and IHC. It is suitable to detect SARS-CoV-2 ORF8 in samples from SARS Coronavirus-2 (SARS-CoV-2).

Quick Overview for SARS-CoV-2 ORF8 antibody (C-Term) (ABIN6992307)

Target: SARS-CoV-2 ORF8

Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARS-CoV-2 ORF8 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SARS-CoV-2 ORF8 Antibody

Binding Specificity: C-Term

Specificity: ORF8 Antibody is predicted to not cross-react with other coronavirus family members.

Purification: SARS-CoV-2 (COVID-19) ORF8 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-SARS-CoV-2 (COVID-19) ORF8 antibody was raised against a peptide corresponding to 14 amino acids near carboxyl terminus of SARS-CoV-2 (COVID-19) ORF8 protein. The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) ORF8 protein.

Isotype: IgG

Application Details

Application Notes: WB: 1 μ,g/mL, IHC: 0.1 μ,g/mL Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) ORF8 antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. It can detect SARS-CoV-2 ORF8 recombinant protein by ELISA and WB. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SARS-CoV-2 (COVID-19) ORF8 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SARS-CoV-2 (COVID-19) ORF8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SARS-CoV-2 ORF8

Target: SARS-CoV-2 ORF8

Target Type: Viral Protein

Background: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8, ORF9b, ORF9c and ORF10. ORF8 may play a role in modulating host immune response (Probable). May play a role in blocking host IL17 cytokine by its interaction with host IL17RA (3).

Molecular Weight: 14kD kDa

Gene ID: 43740577

UniProt: P0DTC8