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CYP3A4 antibody (AA 344-497)

This anti-CYP3A4 antibody is a Rabbit Polyclonal antibody detecting CYP3A4 in WB, IHC, IP and ICC. Suitable for Human.
Catalog No. ABIN7435469

Quick Overview for CYP3A4 antibody (AA 344-497) (ABIN7435469)

Target

See all CYP3A4 Antibodies
CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

Reactivity

  • 74
  • 16
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Human

Host

  • 65
  • 10
  • 1
Rabbit

Clonality

  • 60
  • 16
Polyclonal

Conjugate

  • 52
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
This CYP3A4 antibody is un-conjugated

Application

  • 46
  • 26
  • 24
  • 9
  • 8
  • 7
  • 7
  • 5
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
  • Binding Specificity

    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 344-497

    Purpose

    Polyclonal Antibody to Cytochrome P450 3A4 (CYP3A4)

    Specificity

    The antibody is a rabbit polyclonal antibody raised against CYP3A4. It has been selected for its ability to recognize CYP3A4 in immunohistochemical staining and western blotting.

    Cross-Reactivity

    Pig, Rat

    Purification

    Antigen-specific affinity chromatography followed by Protein A affinity chromatography

    Immunogen

    Recombinant Cytochrome P450 3A4 (CYP3A4) corresdonding to Pro344~Asp497 with N-terminal His Tag

    Isotype

    IgG
  • Application Notes

    Western blotting: 0.01-3 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

    Comment

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.45 mg/mL

    Buffer

    0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

    Expiry Date

    24 months
  • Target

    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

    Alternative Name

    CYP3A4

    Background

    CYP3A3, CYPIIIA4, 1,8-cineole 2-exo-monooxygenase, Albendazole sulfoxidase, Nifedipine oxidase, Quinine 3-monooxygenase, Taurochenodeoxycholate 6-alpha-hydroxylase

    UniProt

    P08684

    Pathways

    Steroid Hormone Biosynthesis
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