PTPN2 antibody (AA 1-257)

Catalog No. ABIN7444958

This Rabbit Polyclonal antibody specifically detects PTPN2 in WB, IHC, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for PTPN2 antibody (AA 1-257) (ABIN7444958)

Target: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-PTPN2 Antibody

Binding Specificity: AA 1-257

Purpose: Polyclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2)

Specificity: The antibody is a rabbit polyclonal antibody raised against PTPN2. It has been selected for its ability to recognize PTPN2 in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) corresdonding to Met1~Gly257

Isotype: IgG

Application Details

Application Notes: Western blotting: 1-5 μg/mL,Immunocytochemistry in formalin fixed cells: 5-20 μg/mL,Immunohistochemistry in formalin fixed frozen section: 5-20 μg/mL,Immunohistochemistry in paraffin section: 5-20 μg/mL,Enzyme-linked Immunosorbent Assay: 0.05-2 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for PTPN2

Target: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Alternative Name: PTPN2

Background: PTPT, TC-PTP, TCELLPTP, TCPTP, T-cell protein-tyrosine phosphatase

UniProt: P17706

Pathways: EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling