PDE4B antibody (AA 500-736)

Catalog No. ABIN7442141

This Rabbit Polyclonal antibody specifically detects PDE4B in WB and IHC. It exhibits reactivity toward Rat.

Quick Overview for PDE4B antibody (AA 500-736) (ABIN7442141)

Target: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PDE4B Antibody

Binding Specificity: AA 500-736

Purpose: Polyclonal Antibody to Phosphodiesterase 4B, cAMP Specific (PDE4B)

Specificity: The antibody is a rabbit polyclonal antibody raised against PDE4B. It has been selected for its ability to recognize PDE4B in immunohistochemical staining and western blotting.

Cross-Reactivity: Human, Mouse

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Phosphodiesterase 4B, cAMP Specific (PDE4B) corresdonding to Lys500~Thr736 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for PDE4B

Target: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Alternative Name: PDE4B

Background: DPDE4, PDE32, Dunce(Drosophila)Homolog Phosphodiesterase E4, cAMP-specific 3',5'-cyclic phosphodiesterase 4B

UniProt: P14646

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction