Chromogranin A antibody

Catalog No. ABIN7234264

This anti-Chromogranin A antibody is a Rabbit Polyclonal antibody detecting Chromogranin A in IHC and WB. Suitable for Human and Mouse.

Quick Overview for Chromogranin A antibody (ABIN7234264)

Target: Chromogranin A (CHGA)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Chromogranin A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-Chromogranin A Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogen: Recombinant Mouse Chromogranin-A protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000 IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Chromogranin A

Target: Chromogranin A (CHGA)

Alternative Name: Chromogranin A

Background: Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin,pancreastatin,catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) ,and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.

Molecular Weight:

Observed_MW: 51 kDa

Calculated_MW: 51 kDa

UniProt: P26339

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling