MCAM antibody

Catalog No. ABIN6999958

This anti-MCAM antibody is a Rabbit Polyclonal antibody detecting MCAM in IHC and WB. Suitable for Human, Mouse and Rat.

Quick Overview for MCAM antibody (ABIN6999958)

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCAM antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-MCAM Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Cell surface glycoprotein MUC18 protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MCAM

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Alternative Name: CD146

Background: CD146,also known as melanoma cell adhesion molecule (MCAM) or MUC18,originally identified as a biomarker of melanoma progression,is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally,it consists of five Ig domains,a transmembrane domain,and a cytoplasmic region. In normal adult tissue,CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis,and has been used as marker of circulating endothelium cells (CECs) .

Molecular Weight:

Observed_MW: 57,71 kDa

Calculated_MW: 57,71 kDa

Gene ID: 4162

UniProt: P43121