SERPINB2 antibody
Quick Overview for SERPINB2 antibody (ABIN7234543)
Target
See all SERPINB2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen Affinity Purification
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Immunogen
- Recombinant Mouse Plasminogen activator inhibitor 2, macrophage protein
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
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Alternative Name
- SERPINB2
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Target Type
- Amino Acid
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Background
- Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor that inactivates tPA and urokinase. It is present in most cells, especiallymonocytes/macrophages. PAI-2 exists in two forms, a 60- kDa extracellular glycosylated form and a 43- kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy.
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Molecular Weight
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Observed_MW: 46 kDa
Calculated_MW: 46 kDa
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Gene ID
- 18788
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UniProt
- P12388
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Pathways
- Autophagy
Target
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