The Rabbit Polyclonal anti-GUCY1A1 antibody has been validated for ELISA and IHC. It is suitable to detect GUCY1A1 in samples from Human, Rat and Mouse.
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.