THOC7 antibody
Quick Overview for THOC7 antibody (ABIN7236184)
Target
See all THOC7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human THOC7
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:25-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.3 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- THOC7 (THO Complex 7 (THOC7))
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Alternative Name
- THOC7
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Background
- NIF3L1 BP1 (Ngg1-interacting factor 3-like 1 binding protein 1), also known as THOC7 (THO complex subunit 7 homolog), fSAP24 or hTREX30, is a 204 amino acid cytoplasmic and nuclear protein that belongs to the THOC7 family and interacts with NIF3L1. NIF3L1 BP1 is a component of the THO/TREX complex that is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling Pol II with RNA splicing and export factors. The THO/TREX complex also plays a role in the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The gene that encodes NIF3L1 BP1 maps to human chromosome 3p14.1.
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Molecular Weight
- 24 kDa
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UniProt
- Q6I9Y2
Target
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