AURKAIP1 antibody

Catalog No. ABIN7236305

The Rabbit Polyclonal anti-AURKAIP1 antibody (ABIN7236305) specifically detects AURKAIP1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for AURKAIP1 antibody (ABIN7236305)

Target: AURKAIP1 (Aurora Kinase A Interacting Protein 1 (AURKAIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AURKAIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AURKAIP1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human AURKAIP1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AURKAIP1

Target: AURKAIP1 (Aurora Kinase A Interacting Protein 1 (AURKAIP1))

Alternative Name: AURKAIP1

Background: AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Molecular Weight: 22 kDa

UniProt: Q9NWT8