GAB2 antibody
Quick Overview for GAB2 antibody (ABIN7237045)
Target
See all GAB2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human GAB2
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Isotype
- IgG
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anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 273-484) antibody
GAB2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pTyr452) antibodyGAB2 Reactivity: Human, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pSer159) antibodyGAB2 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (Ser159) antibodyGAB2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 3-30), (N-Term) antibodyGAB2 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB21209 unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 357-607) antibodyGAB2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 601-676) antibodyGAB2 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pSer623) antibodyGAB2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pTyr643) antibodyGAB2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (C-Term) antibodyGAB2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.3 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
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Alternative Name
- GAB2
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Background
- This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
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Molecular Weight
- 74 kDa
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UniProt
- Q9UQC2
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
Target
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