PYGL antibody

Catalog No. ABIN7237619

The Rabbit Polyclonal anti-PYGL antibody (ABIN7237619) specifically detects PYGL in WB, IHC and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for PYGL antibody (ABIN7237619)

Target: PYGL (phosphorylase, Glycogen, Liver (PYGL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYGL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PYGL Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PYGL

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:30-1:150

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PYGL

Target: PYGL (phosphorylase, Glycogen, Liver (PYGL))

Alternative Name: PYGL

Background: This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.

Molecular Weight: 97 kDa

UniProt: P06737

Pathways: Carbohydrate Homeostasis, Cellular Glucan Metabolic Process