SMARCB1
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
3C4
unconjugated
Application Notes
WB 1:500-1:2000, IHC 1:25-1:100
Restrictions
For Research Use only
Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
SMARCB1
(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))
Alternative Name
SMARCB1
Background
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated witHuman, Mousealignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.