ADCY5 antibody

Catalog No. ABIN7238498

The Rabbit Polyclonal anti-ADCY5 antibody (ABIN7238498) specifically detects ADCY5 in ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ADCY5 antibody (ABIN7238498)

Target: ADCY5 (Adenylate Cyclase 5 (ADCY5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ADCY5 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human ADCY5

Isotype: IgG

Application Details

Application Notes: IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADCY5

Target: ADCY5 (Adenylate Cyclase 5 (ADCY5))

Alternative Name: ADCY5

Background: This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.

NCBI Accession: NP_001186571

UniProt: O95622

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma